Panama Canal

Considered one of the Seven Wonders of the Industrial World, the Panama Canal provides a unique opportunity to cruise between the Caribbean and the Pacific Ocean.

Considered one of the Seven Wonders of the Industrial World, the Panama Canal provides a unique opportunity to cruise between the Caribbean and the Pacific Ocean. Some Caribbean cruises will include just a partial transit of the canal up to Gatun Lake, but others will have a full transit included, generally including ports in Coastal Mexico, Central America and the Southern Caribbean.

When to visit?
Most cruises will cruise through the Panama Canal in the northern winter, from October to April when the weather is generally warmer and it is the dry season in Central America.

Discover more about Panama Canal Cruises

Setting off from Miami, cruises to the southern Caribbean will call into to Curacao and Aruba, colourful Jamaica and Cartagena in Columbia before entering the Panama Canal.

Cruising the Panama Canal is one of cruising's most unforgettable experiences - a 51 mile crossing taking a full day between Panama City on the Pacific side through to Colon in the Caribbean. By an amazing feat of mechanics and on-shore "mule" locomotives, the "Big Ditch" lifts your cruise ship through three great locks before you travese man-made lakes, channels which have been blasted through rock and dense, tropical jungle.

On the Pacific side of the Panama Canal, you will generally call into Acapulco and Cabo San Lucas in Mexico. Heading further south you may visit San Jose from Puntarenas, from where you can explore the rainforests and mountains of Costa Rica. Heading into Puerto Quetzal you can visit the Mayan ruins in Guatemala.

Ports

Panama Canal

We found

228 cruises

Oosterdam, Panama Canal
1 / 21
6 % off
Holland America Line
Duration
16 nights
Date
18 Nov 2026
Ship
Oosterdam
  • Departure - Fort Lauderdale, Florida
  • 13 stops  
  • Arrival - Valparaiso, Chile
£1449
From
£1363
Price per person / inside stateroom
Le Bellot, Panama Canal
1 / 14
Ponant
Duration
10 nights
Date
21 Nov 2026
Ship
Le Bellot
  • Departure - Colón, Panama
  • 12 stops  
  • Arrival - Puntarenas, Costa Rica
From
£7127
Price per person / balcony stateroom
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
18 nights
Date
24 Nov 2026
Ship
Wind Star
  • Departure - Bridgetown, Barbados
  • 15 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£6066
Price per person / oceanview stateroom
Crown Princess, Panama Canal
1 / 20
Discount
Princess Cruises
Duration
16 nights
Date
3 Dec 2026
Ship
Crown Princess
  • Departure - Los Angeles, USA
  • 9 stops  
  • Arrival - Fort Lauderdale, Florida
£949
From
£912
Price per person / inside stateroom
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
16 nights
Date
4 Dec 2026
Ship
Star Legend
  • Departure - Bridgetown, Barbados
  • 12 stops  
  • Arrival - Balboa, Fuerte Amador, Panama
From
£3861
Price per person / suite
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
5 Dec 2026
Ship
Wind Star
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£2597
Price per person / oceanview stateroom
Le Bellot, Panama Canal
1 / 14
Ponant
Duration
10 nights
Date
8 Dec 2026
Ship
Le Bellot
  • Departure - Puntarenas, Costa Rica
  • 13 stops  
  • Arrival - Colón, Panama
From
£6450
Price per person / balcony stateroom
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
8 nights
Date
12 Dec 2026
Ship
Star Legend
  • Departure - Oranjestad, Aruba
  • 6 stops  
  • Arrival - Balboa, Fuerte Amador, Panama
From
£2419
Price per person / suite
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
12 Dec 2026
Ship
Wind Star
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 6 stops  
  • Arrival - Colón, Panama
From
£2623
Price per person / oceanview stateroom
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
16 nights
Date
12 Dec 2026
Ship
Star Legend
  • Departure - Oranjestad, Aruba
  • 13 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£4193
Price per person / suite
Azamara Quest, Panama Canal
1 / 14
Discount
Azamara
Duration
18 nights
Date
18 Dec 2026
Ship
Azamara Quest
  • Departure - Miami, Florida, USA
  • 9 stops  
  • Arrival - San Francisco, USA
£2149
From
£2064
Price per person / inside stateroom
Available promotion:
Receive up to $750 onboard credit per stateroom.*
Le Bellot, Panama Canal
1 / 14
Ponant
Duration
10 nights
Date
18 Dec 2026
Ship
Le Bellot
  • Departure - Colón, Panama
  • 12 stops  
  • Arrival - Puntarenas, Costa Rica
From
£7127
Price per person / balcony stateroom
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
19 Dec 2026
Ship
Wind Star
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£2597
Price per person / oceanview stateroom
Insignia, Panama Canal
1 / 12
Oceania Cruises
Duration
15 nights
Date
19 Dec 2026
Ship
Insignia
  • Departure - Miami, Florida, USA
  • 11 stops  
  • Arrival - Callao (Lima), Peru
From
£3289
Price per person / inside stateroom
Le Lapérouse, Panama Canal
1 / 13
Ponant
Duration
10 nights
Date
19 Dec 2026
Ship
Le Lapérouse
  • Departure - Colón, Panama
  • 12 stops  
  • Arrival - Puntarenas, Costa Rica
From
£6793
Price per person / balcony stateroom
Silver Dawn, Panama Canal
1 / 20
Silversea
Duration
18 nights
Date
21 Dec 2026
Ship
Silver Dawn
  • Departure - Miami, Florida, USA
  • 9 stops  
  • Arrival - Los Angeles, USA
From
£21550
Price per person / suite
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
26 Dec 2026
Ship
Wind Star
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 6 stops  
  • Arrival - Colón, Panama
From
£3457
Price per person / oceanview stateroom
Island Princess, Panama Canal
1 / 14
Discount
Princess Cruises
Duration
16 nights
Date
28 Dec 2026
Ship
Island Princess
  • Departure - Los Angeles, USA
  • 9 stops  
  • Arrival - Fort Lauderdale, Florida
£2340
From
£2247
Price per person / balcony stateroom
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
8 nights
Date
28 Dec 2026
Ship
Star Legend
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 7 stops  
  • Arrival - Colón, Panama
From
£2413
Price per person / suite
Seven Seas Grandeur, Panama Canal
1 / 9
Regent Seven Seas Cruises
Duration
16 nights
Date
29 Dec 2026
Ship
Seven Seas Grandeur
  • Departure - Miami, Florida, USA
  • 9 stops  
  • Arrival - Los Angeles, USA
From
£11339
Price per person / suite
Zuiderdam, Panama Canal
1 / 24
6 % off
Holland America Line
Duration
14 nights
Date
2 Jan 2027
Ship
Zuiderdam
  • Departure - Miami, Florida, USA
  • 9 stops  
  • Arrival - San Diego, USA
£1449
From
£1363
Price per person / inside stateroom
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
2 Jan 2027
Ship
Wind Star
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£2493
Price per person / oceanview stateroom
Zaandam, Panama Canal
1 / 23
6 % off
Holland America Line
Duration
41 nights
Date
3 Jan 2027
Ship
Zaandam
  • Departure - Fort Lauderdale, Florida
  • 32 stops  
  • Arrival - Buenos Aires, Argentina
£7899
From
£7426
Price per person / inside stateroom
Zaandam, Panama Canal
1 / 23
6 % off
Holland America Line
Duration
70 nights
Date
3 Jan 2027
Ship
Zaandam
  • Departure - Fort Lauderdale, Florida
  • 49 stops  
  • Arrival - Fort Lauderdale, Florida
£11399
From
£10716
Price per person / inside stateroom
Le Bellot, Panama Canal
1 / 14
Ponant
Duration
10 nights
Date
4 Jan 2027
Ship
Le Bellot
  • Departure - Puntarenas, Costa Rica
  • 12 stops  
  • Arrival - Colón, Panama
From
£7127
Price per person / balcony stateroom
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
7 nights
Date
5 Jan 2027
Ship
Star Legend
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£2145
Price per person / suite
Le Lapérouse, Panama Canal
1 / 13
Ponant
Duration
10 nights
Date
5 Jan 2027
Ship
Le Lapérouse
  • Departure - Puntarenas, Costa Rica
  • 12 stops  
  • Arrival - Colón, Panama
From
£7127
Price per person / balcony stateroom
Queen Victoria, Panama Canal
1 / 26
Discount
Cunard
Duration
26 nights
Date
10 Jan 2027
Ship
Queen Victoria
  • Departure - Southampton, Great Britain
  • 9 stops  
  • Arrival - Los Angeles, USA
£2299
From
£2254
Price per person / inside stateroom
Available promotion:
The Cunard Black Friday Event - 10% off selected 2027 voyages!*
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
7 nights
Date
12 Jan 2027
Ship
Star Legend
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 6 stops  
  • Arrival - Colón, Panama
From
£2145
Price per person / suite
Seven Seas Splendor, Panama Canal
1 / 9
Regent Seven Seas Cruises
Duration
14 nights
Date
12 Jan 2027
Ship
Seven Seas Splendor
  • Departure - Miami, Florida, USA
  • 11 stops  
  • Arrival - Panama City, Panama
From
£12089
Price per person / suite
Seven Seas Splendor, Panama Canal
1 / 9
Regent Seven Seas Cruises
Duration
42 nights
Date
12 Jan 2027
Ship
Seven Seas Splendor
  • Departure - Miami, Florida, USA
  • 25 stops  
  • Arrival - Papeete (Tahiti), French Polynesia
From
£30739
Price per person / suite
Le Bellot, Panama Canal
1 / 14
Ponant
Duration
10 nights
Date
14 Jan 2027
Ship
Le Bellot
  • Departure - Colón, Panama
  • 13 stops  
  • Arrival - Puntarenas, Costa Rica
From
£8138
Price per person / balcony stateroom
Le Lapérouse, Panama Canal
1 / 13
Ponant
Duration
7 nights
Date
15 Jan 2027
Ship
Le Lapérouse
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puntarenas, Costa Rica
From
£4763
Price per person / balcony stateroom
Seabourn Quest, Panama Canal
1 / 12
Seabourn
Duration
23 nights
Date
17 Jan 2027
Ship
Seabourn Quest
  • Departure - Callao (Lima), Peru
  • 11 stops  
  • Arrival - Papeete (Tahiti), French Polynesia
From
£7648
Price per person / suite
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
7 nights
Date
19 Jan 2027
Ship
Star Legend
  • Departure - Colón, Panama
  • 7 stops  
  • Arrival - Puerto Caldera (Puntarenas), Costa Rica
From
£2145
Price per person / suite
Queen Anne, Panama Canal
1 / 35
Discount
Cunard
Duration
56 nights
Date
22 Jan 2027
Ship
Queen Anne
  • Departure - Fort Lauderdale, Florida
  • 30 stops  
  • Arrival - Fort Lauderdale, Florida
£6609
From
£6477
Price per person / inside stateroom
Queen Anne, Panama Canal
1 / 35
Discount
Cunard
Duration
56 nights
Date
22 Jan 2027
Ship
Queen Anne
  • Departure - Fort Lauderdale, Florida
  • 30 stops  
  • Arrival - Fort Lauderdale, Florida
£7909
From
£7751
Price per person / inside stateroom
Wind Star, Panama Canal
1 / 12
Windstar Cruises
Duration
7 nights
Date
24 Jan 2027
Ship
Wind Star
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 6 stops  
  • Arrival - Colón, Panama
From
£3875
Price per person / oceanview stateroom
Seven Seas Grandeur, Panama Canal
1 / 9
Regent Seven Seas Cruises
Duration
16 nights
Date
24 Jan 2027
Ship
Seven Seas Grandeur
  • Departure - Los Angeles, USA
  • 8 stops  
  • Arrival - Miami, Florida, USA
From
£10919
Price per person / suite
Star Legend, Panama Canal
1 / 19
Windstar Cruises
Duration
7 nights
Date
26 Jan 2027
Ship
Star Legend
  • Departure - Puerto Caldera (Puntarenas), Costa Rica
  • 6 stops  
  • Arrival - Colón, Panama
From
£2145
Price per person / suite
40 of 228 pcs